Hi Josh - this error is most likely just telling you that CPLEX ran out of memory. There's not much you can do about that short of buying more RAM for your PC.
But I would suggest starting by making a smaller problem to solve and then work your way up until the system crashes. That way you can find out where you stand. To make a smaller model, trying some of the following: choose an earlier end year, or reduce the number of time slices in your model. You can also reduce other dimensions such as the number of regions or the number processes, but this take a bit more work.
BTW - when reporting errors, it is always good to note your system specs (e.g. which version of Windows, LEAP, NEMO, etc. and how much RAM you have). You can get all that info in one handy place on the LEAP Help: About screen.